Paraiso

Uses

The root was official in the U. S. P., 1880, as an anthelmintic; it is administered in the following form:

[table omitted; see the source text]

Boil till reduced one half.

Dose

For a child 1 soup-spoonful every 15 minutes till nausea is produced.

In view of the narcotic effects produced by this drug, the foregoing method of administration seems to us imprudent; we prefer to give 30–70 grams of the decoction and follow with a purgative such as castor oil.

This drug is also tonic, febrifuge and astringent, and a decoction of its leaves and flowers is used as a wash for ulcers. Some believe that the leaves and fruit contain toxic principles, which may well be true considering the effects of large doses of their preparations. It has also been observed that the bark collected in March and April may cause dilatation of the pupil, stupor, etc.; this may be explained by the fact that at this season the sap is rising in the tree and the bark contains an increased amount of active ingredients.

The fruit yields a fixed oil, and by fermentation and distillation produces alcohol.

The root bark referred to is bitter and nauseous, if taken from the superficial roots—the part usually employed; the bark of the deeper parts is astringent by virtue of the contained tannin.

Jacobs analyzed the bark and isolated an amorphous resin of yellowish color and very bitter taste. It is soluble in alcohol, ether and chloroform, slightly soluble in sulphuret of carbon, insoluble in turpentine or benzin. He believes that it is the active principle of the root, and produces the anthelmintic action already mentioned: the proper dose is 0.20 centigrams to a child of 4 years, followed by a purge of calomel.

Botanical description

A tree, 30–40° high, with leaves alternate, compound, odd-pinnate; leaflets opposite, ovate, pointed, dentate. Flowers in large axillary compound panicles. Calyx, 5 sepals. Corolla, 5 petals, rose-colored within, lilac-colored without. Stamens 10, united into a cylindrical tube, expanded at both ends, the mouth 15-toothed. Anthers inserted near the apex of the tube, short, fleshy, bilocular. Ovary free, of 5 biovuled cells. Style of equal length with the tube. Stigma button-shaped. Fruit a drupe, about the size of a small olive, yellow when ripe, with a dark brown pit of 5 one-seeded cells.